If you're like most successful professionals in an active career search without getting a response, it most likely your resume is not good enough. Employers get a 1000+ resumes for every position they post publicly.
It is essential that your resume is more than just a nicely formatted documentation of your experience and credential. As a professional, you need a resume that compels the decision maker to respond like they have just read an advert. If this is missing from your resume, it explains the lack of response you are getting.
The real intention of the resume is not to get you a job but a phone call. So the document does not need to overload them with everything you have done.
You need to give employers the highlights of your strengths and achievements that they are curious enough to give you a phone call to learn more about you.
In order to do this most effectively, I make a functional resume that displays client unique combination of strengths, achievements and education, and their unique value proposition. When this is done, they are positioned as an investment that will pay great ROI for the company that hires you.